This book provides an integrated overview of key trends in digital transformation, taking into consideration five interrelated dimensions: strategy and business models, society, organization, technology and regulation. As such, it provides a framework for the analysis of digital business transformation and its emerging factors, analyzing twenty-five key trends in terms of their future impact. On that basis, the book then delineates a new approach centered on the mutually accelerating links between multiple value creation spaces. It proposes a new mode of production – accelerated production of links (acceluction) – and analyzes it with respect to the still-dominant concept of lean production. Based on the results of the international CIGREF research program ISD, the book presents a valuable perspective of the expected impact of the abundance of networks and data as critical resources for enterprises beyond 2020.