Promoter and CpG Island Microarrays

  • DNA Press
  • 2005
  • Paperback
  • 320
  • Sproget er ikke defineret
  • 1
  • 9780974876566
0

Promoter binding analysis has largely been a laborious and inefficient process. With the advent of "ChIP on chip" (Chromatin Immunoprecipitation on Microarrays or Chips) the research community has been given a new, powerful and high throughput option. This book aims to not only introduce the power of this technology but specifically to provide detailed protocols as to how to perform a ChIP on chip experiment. This book will provide the reader a number of benefits: * Detailed explanations of the Chromatin Immunoprecipitation technique * Protocols for performing ChIP on chip experiments * Informatics approaches to identifying promoter regions in genomic DNA * Guidelines for analyzing the data that is obtained from a ChIP on chip experiment * Techniques for methylation analysis of CpG islands using CpG microarrays * Indications of future directions for improvements to the technology including the development of promoter specific arrays, and regulatory region arrays (enhancers and suppressors).

350,00 kr.