The two volume set LNCS 13052 and 13053 constitutes the refereed proceedings of the 19th International Conference on Computer Analysis of Images and Patterns, CAIP 2021, held virtually, in September 2021.   The 87 papers presented were carefully reviewed and selected from 129 submissions. The papers are organized in the following topical sections across the 2 volumes: 3D vision, biomedical image and pattern analysis; machine learning; feature extractions; object recognition; face and gesture, guess the age contest, biometrics, cryptography and security; and segmentation and image restoration.